Phenoscaping Reveals Multimodal γδ T Cell Cytotoxicity as a Strategy to Overcome Cancer Cell-Mediated Immunomodulation
C. Nattress, R. O’Sullivan, D. Fowler, C. Hutton, P. Vlckova, J. Sufi, M. Buschhaus, E. Basiarz, M.R. Zapatero, F.C. Rodriguez, X. Qin, A. Campbell, A. Kanouta, V.S.W. Li, K. Chester, J. Anderson, M. Barisa, J.P. Fisher, C.J. Tape
Cancer Research (in press)

High-dimensional Signalling Analysis of Organoids
A. Dobric, C.J. Tape
Current Opinion in Cell Biology (2025)

Oncogenic PIK3CA Corrupts Growth Factor Signaling Specificity
R.R. Madsen, A. Le Marois, O. Mruk, M. Voliotis, S. Yin, J. Sufi, X. Qin, S.J. Zhao, J. Gorczynska, D. Morelli, L. Davidson, E. Sahai, V.I. Korolchuk, C.J. Tape, B. Vanhaesebroeck
Molecular Systems Biology (2024)

The MondoA-dependent TXNIP/GDF15 Axis Predicts Oxaliplatin Response in Colorectal Adenocarcinomas
J. Deng*, T. Pan*, D. Wang, Y. Hong, Z. Liu, X. Zhou, Z. An, L. Li, G. Alfano, G. Li, L. Dolcetti, R. Evans, J.M .Vicencio, P. Vlckova, Y. Chen, J. Monypenny, C.A. De Carvalho Gomes, G. Weitsman, K. Ng, C. McCarthy, X. Yang, Z. Hu, J.C. Porter, C.J. Tape, M. Yin, F. Wei, M. Rodriguez-Justo, J. Zhang, S. Tejpar, R. Beatson, T. Ng
EMBO Molecular Medicine (2024)

Payload-delivering Engineered γδ T cells Display Enhanced Cytotoxicity, Persistence, and Efficacy in Preclinical Models of Osteosarcoma
D. Fowler, M. Barisa, A.S. Navarrete, C. Nattress, E. Hawkins, E. Vassalou, A. Kanouta, J. Counsell, E.M. Rota, P. Vlckova, B. Draper, T. De Mooij, H. Brezovjakova, A.T. Baker, K. Schotland, M.C. Manara, C.J. Tape, K. Chester, J. Anderson, J. Fisher
Science Translation Medicine (2024)

Functional Analysis of Cell Plasticity Using Single-cell Technologies
X. Qin, C.J. Tape
Trends in Cell Biology (2024)

An Oncogenic Phenoscape of Colonic Stem Cell Polarisation
X. Qin*, F.C. Rodriguez*, J. Sufi, P. Vlckova, J. Claus, C.J. Tape
Cell (2023)

Trellis Tree-based Analysis Reveals Stromal Regulation of Patient-Derived Organoid Drug Responses
M.R. Zapatero*, A. Tong*, J.W. Opzoomer, R. O’Sullivan, F.C. Rodriguez, J. Sufi, P. Vlckova, C. Nattress, X. Qin, J. Claus, D. Hochhauser, S. Krishnaswamy, C.J. Tape
Cell (2023)

Plastic Persisters: Revival Stem Cells in Colorectal Cancer
C.J. Tape
Trends in Cancer (2023)

Activation Priming and Cytokine Polyfunctionality Modulate the Enhanced Functionality of Low-Affinity CD19 CAR T Cells
I.M. Michelozzi, E. Gomez-Castaneda, R.V.C. Pohle, F.C. Rodriguez, J. Sufi, P. Puigdevall-Costa, M. Subramaniyam, E. Kirtsios, A. Eddaoudi, S.W. Wu, A. Guvenel, J. Fisher, S. Ghorashian, M. Pule, C.J. Tape, S. Castellano, P.J. Amrolia, A. Giustacchini
Blood Advances (2022)

High-Dimensional Functional Phenotyping of Preclinical Human CAR T Cells Using Mass Cytometry
I.M. Michelozzi, J. Sufi, T.A. Adejumo, P.J. Amrolia, C.J. Tape, A. Giustacchini
STAR Protocols (2022)

Multiplexed Single-Cell Analysis of Organoid Signaling Networks
J. Sufi*, X. Qin*, F.C. Rodriguez, Y.J. Bu, P. Vlckova, M.R. Zapatero, M. Nitz, C.J. Tape
Nature Protocols (2021)

Intra- and Intercellular Signaling Pathways Associated with Drug-induced Cardiac Pathophysiology
F. Guo, A. Hall, C.J. Tape, S. Ling, A. Pointon
Trends in Pharmacological Sciences (2021)

Deciphering Organoids: High-Dimensional Analysis of Biomimetic Cultures
X. Qin, C.J. Tape
Trends in Biotechnology (2021)

Cell-Type Specific Signaling Networks in Heterocellular Organoids
X. Qin, J. Sufi*, P. Vlckova*, P. Kyriakidou*, S.E. Acton, V.S.W. Li, M. Nitz, C.J. Tape
Nature Methods (2020)

Cross-talk with Lung Epithelial Cells Regulates Sfrp2-mediated Latency in Breast Cancer Dissemination
M. Montagner, R. Bhome, S. Hooper, P. Chakravarty, X. Qin, J. Sufi, A. Bhargava, C.D.H. Ratcliffe, Y. Naito, A. Pocaterra, C.J. Tape, E. Sahai
Nature Cell Biology (2020)

Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
J.L. Orgaz, E. Crosas-Molist, A. Sadok, A. Perdrix-Rosell, O. Maiques, I. Rodriguez-Hernandez, J. Monger, S. Mele, M. Georgouli, V. Bridgeman, P. Karagiannis, R. Lee, P. Pandya, L. Boehme, F. Wallberg, C.J. Tape, S.N. Karagiannis, I. Malanchi, V. Sanz-Moreno
Cancer Cell (2020)

Fibroblastic Reticular Cells Control Conduit Matrix Deposition during Lymph Node Expansion
V.G. Martinez, V. Pankova, L. Krasny, T. Singh, S. Makris, I.J. White, A.C. Benjamin, S. Dertschnig, H.L. Horsnell, J. Kriston-Vizi, J.J. Burden, P.H. Huang, C.J. Tape, S.E. Acton
Cell Reports (2019)

Cell-Specific Labelling For Analysing Bidirectional Signalling by Mass Spectrometry
C.J. Tape & C. Jørgensen
Kinase Signaling Networks, Methods in Mol. Bio. (2017)

The Heterocellular Emergence of Colorectal Cancer
C.J. Tape
Trends in Cancer (2017)

Proteomics Profiling of Interactome Dynamics by Colocalisation Analysis (COLA)
F.K. Mardakheh, H.Z. Sailem, S. Kümper, C.J. Tape, R.R. McCully, A. Paul, S. Anjomani-Virmouni, C. Jørgensen, G. Poulogiannis, C.J. Marshall, C. Bakal
Molecular BioSystems. (2016)

Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation
C.J. Tape, S. Ling, M. Dimitriadi, K.M. McMahon, J.D. Worboys, H.S. Leong, I.C. Norrie, C.J. Miller, G. Poulogiannis, D.A. Lauffenburger, C. Jørgensen
Cell (2016)