Publications

Pre-Print

  • X. Qin, J. Sufi*, P. Vlckova*, P. Kyriakidou*, S. E. Acton, V. S. W. Li, M. Nitz, C. J. Tape, “Single-Cell Signalling Analysis of Heterocellular Organoids”, bioRxiv (2019) DOI / PDF

  • V. G. Martinez, V. Pankova, L. Krasny, T. Singh, I. J. White, A. C. Benjamin, S. Dertschnig, H. L. Horsnell, J. Kriston-Vizi, J. J. Burden, P. H. Huang, C. J. Tape, S. E. Acton, “Conduit Integrity is Compromised During Acute Lymph Node Expansion”, bioRxiv (2019) DOI / PDF

Peer-Reviewed

  • C. J. Tape & C. Jørgensen, "Cell-Specific Labelling For Analysing Bidirectional Signalling by Mass Spectrometry", Kinase Signaling Networks, Methods in Mol. Bio. (2017) 1636: 219-234. PMID: 28730482  PDF

  • C. J. Tape, "The Heterocellular Emergence of Colorectal Cancer"Trends in Cancer (2017) 3(2): 79-88. PMID: 28239669  PDF

  • F.K. Mardakheh, H.Z. Sailem, S. Kümper, C. J. Tape, R.R. McCully, A. Paul, S. Anjomani-Virmouni, C. Jørgensen, G. Poulogiannis, C.J. Marshall, C. Bakal, "Proteomics Profiling of Interactome Dynamics by Colocalisation Analysis (COLA)", Mol. BioSys. (2016). PMID 27824369  PDF

  • C. J. Tape, "Systems Biology Analysis of Heterocellular Signaling"Trends in Biotechnology (2016) 34(8). PMID: 27087613  PDF

  • C. J. Tape, S. Ling, M. Dimitriadi, K.M. McMahon, J.D. Worboys, H.S. Leong, I.C. Norrie, C.J. Miller, G. Poulogiannis, D.A. Lauffenburger, C. Jørgensen, "Oncogenic KRAS Regulates Tumor Cell Signaling via Stromal Reciprocation"Cell (2016) 165(4): 910–920 PMID: 27087446  PDF 

  • R. Natrajan, H. Sailem , F.K. Mardakheh, M.A. Garcia, C. J. Tape, M. Dowsett, C. Bakal, Y. Yuan, "Microenvironmental Heterogeneity Parallels Breast Cancer Progression: A Histology-Genomic Integration Analysis", PLOS Medicine (2016) Feb 16;13(2). PMID 26881778 PDF

  • S. Santamaria, K. Yamamoto, K.A. Botkjaer, C. J. Tape, M.R. Dyson, J. McCafferty, G. Murphy, H. Nagase, "Antibody-based exosite inhibitors of ADAMTS-5 (Aggrecanase-2)"Biochem. J. (2015) Aug 24. PMID 26303525  PDF

  • F. Caiazza, P. M. McGowan, M. Mullooly, A. Murray, N. Synnott, N. O'Donovan, L. Flanagan, C. J. Tape, G. Murphy, J. Crown, M.J. Duffy, "Targeting ADAM-17 with an inhibitory monoclonal antibody has antitumour effects in triple-negative breast cancer cells"British Journal of Cancer (2015). PMID: 26010411  PDF

  • Y. Huang, N. Benaich, C. J. Tape, H.F. Kwok, G. Murphy, "Targeting the Sheddase Activity of ADAM17 by an Anti-ADAM17 Antibody D1 (A12) Inhibits Head and Neck Squamous Cell Carcinoma Cell Proliferation and Motility via Blockage of Bradykinin Induced HERs Transactivation"Int. J. of Bio. Sci. (2014) Jul 10(7):702-714. PMID: 25013379  PDF

  • C. J. Tape, J.D. Worboys, J. Sinclair, R. Gourlay, J. Vogt, K.M. McMahon, M. Trost, D.A. Lauffenburger, D.J. Lamont, C. Jørgensen, "Reproducible Automated Phosphopeptide Enrichment using Magnetic TiO2 and Ti-IMAC"Analytical Chemistry (2014) 86(20):10296-302. PMID: 25233145  PDF

  • C. J. Tape, I.C. Norrie, J.D. Worboys, L. Lim, D.A. Lauffenburger, C. Jørgensen, "Cell-Specific Labeling Enzymes For Analysis of Cell-Cell Communication in Continuous Co-Culture"Mol. Cell Proteomics (2014) Jul 13(7):1866-76. PMID: 24820872  PDF

  • H.F. Kwok, K.A. Botkjaer, C.J. Tape, Y. Huang, J. McCafferty, G. Murphy, "Development of a 'mouse and human cross-reactive' affinity matured exosite inhibitory antibody specific to TACE (ADAM17) for cancer immunotherapy"PEDS (2014) Apr 10.1093/protein/gzu010. PMID: 24769623  PDF

  • F.M. Richards*, C. J. Tape*, D.I. Jodrell, G. Murphy, "Anti-Tumour Effects of a Specific Anti-ADAM17 Antibody in an Ovarian Cancer Model In Vivo"PLOS One (2012) 7(7):e40597. PMID: 22792380  PDF

  • C. J. Tape, S.H. Willems, S.L. Dombernowsky, P.L. Stanley, M. Fogarasi, W. Ouwehand, J. McCafferty, G. Murphy, "Cross-domain inhibition of TACE ectodomain"PNAS (2011) Apr 5;108(14):5578-83. PMID: 21415364  PDF 

  • L. Woodbine, S. Grigoriadou, A.A. Goodarzi, E. Riballo, C. J. Tape, A.W. Oliver, M.C. van Zelm, M.S. Buckland, E.G. Davies, L.H. Pearl, P.A. Jeggo, "An Artemis polymorphic variant reduces Artemis activity and confers cellular radiosensitivity"DNA Repair (2010) Sep 4;9(9):1003-10. PMID: 20674517  PDF

  • S.H. Willems, C. J. Tape, P.L. Stanley, N.A. Taylor, I.G. Mills, D.E. Neal, J. McCafferty, G. Murphy, "Thiol isomerases negatively regulate the cellular shedding activity of ADAM17",  Biochem. J. (2010) May 27;428(3):439-50. PMID: 20345372  PDF

Patents

  • C. J. Tape, J. McCafferty, G. Murphy, "Anti-TACE Antibody Molecules And Their Uses", WO2012104581, US-9150659-B2 (2012). USPTO

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